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A Simple PCR–RFLP Method for Genetic Phase Determination in Compound Heterozygotes

When susceptibility to diseases is caused by cis-effects of multiple alleles at adjacent polymorphic sites, it may be difficult to assess with confidence the genetic phase and identify individuals carrying the risk haplotype. Experimental assessment of genetic phase is still challenging and most pop...

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Detalles Bibliográficos
Autores principales: Perry, Rodney T., Dwivedi, Harsh, Aissani, Brahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268647/
https://www.ncbi.nlm.nih.gov/pubmed/22303402
http://dx.doi.org/10.3389/fgene.2011.00108