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Experimental procedure for the characterization of radiation damage in macromolecular crystals

A reliable and reproducible method to automatically characterize the radiation sensitivity of macromolecular crystals at the ESRF beamlines has been developed. This new approach uses the slope of the linear dependence of the overall isotropic B-factor with absorbed dose as the damage metric. The met...

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Detalles Bibliográficos
Autores principales: Leal, Ricardo M. F., Bourenkov, Gleb P., Svensson, Olof, Spruce, Darren, Guijarro, Matias, Popov, Alexander N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268693/
https://www.ncbi.nlm.nih.gov/pubmed/21525646
http://dx.doi.org/10.1107/S0909049511002251