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Altered nuclear tRNA metabolism in La-deleted Schizosaccharomyces pombe is accompanied by a nutritional stress response involving Atf1p and Pcr1p that is suppressible by Xpo-t/Los1p

Deletion of the sla1(+) gene, which encodes a homologue of the human RNA-binding protein La in Schizosaccharomyces pombe, causes irregularities in tRNA processing, with altered distribution of pre-tRNA intermediates. We show, using mRNA profiling, that cells lacking sla1(+) have increased mRNAs from...

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Detalles Bibliográficos
Autores principales: Cherkasova, Vera, Lopez Maury, Luis, Bacikova, Dagmar, Pridham, Kevin, Bähler, Jürg, Maraia, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268726/
https://www.ncbi.nlm.nih.gov/pubmed/22160596
http://dx.doi.org/10.1091/mbc.E11-08-0732

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