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Low affinity PEGylated hemoglobin from Trematomus bernacchii, a model for hemoglobin-based blood substitutes

BACKGROUND: Conjugation of human and animal hemoglobins with polyethylene glycol has been widely explored as a means to develop blood substitutes, a novel pharmaceutical class to be used in surgery or emergency medicine. However, PEGylation of human hemoglobin led to products with significantly diff...

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Detalles Bibliográficos
Autores principales:	Coppola, Daniela, Bruno, Stefano, Ronda, Luca, Viappiani, Cristiano, Abbruzzetti, Stefania, di Prisco, Guido, Verde, Cinzia, Mozzarelli, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268738/ https://www.ncbi.nlm.nih.gov/pubmed/22185675 http://dx.doi.org/10.1186/1471-2091-12-66

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