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Application of multiple forms of mechanical loading to human osteoblasts reveals increased ATP release in response to fluid flow in 3D cultures and differential regulation of immediate early genes

ATP is actively released into the extracellular environment from a variety of cell types in response to mechanical stimuli. This is particularly true in bone where mechanically induced ATP release leads to immediate early gene activation to regulate bone remodelling; however there is no consensus as...

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Detalles Bibliográficos
Autores principales: Rumney, R.M.H., Sunters, A., Reilly, G.C., Gartland, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268859/
https://www.ncbi.nlm.nih.gov/pubmed/22176713
http://dx.doi.org/10.1016/j.jbiomech.2011.11.036

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