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The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1

We demonstrate that HPV-16 E7 forms a complex with Miz-1. UV-induced expression of the CDK-inhibitor p21(Cip1) and subsequent cell cycle arrest depends upon endogenous Miz-1 in HPV-negative C33A cervical cancer cells containing mutated p53. Transient expression of E7 in C33A inhibits UV-induced expr...

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Detalles Bibliográficos
Autores principales:	Morandell, Dieter, Kaiser, Andreas, Herold, Steffi, Rostek, Ursula, Lechner, Stefan, Mitterberger, Maria C., Jansen-Dürr, Pidder, Eilers, Martin, Zwerschke, Werner
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Academic Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3268862/ https://www.ncbi.nlm.nih.gov/pubmed/22099967 http://dx.doi.org/10.1016/j.virol.2011.10.027

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