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Coding Constraints Modulate Chemically Spontaneous Mutational Replication Gradients in Mitochondrial Genomes
Distances from heavy and light strand replication origins determine duration mitochondrial DNA remains singlestranded during replication. Hydrolytic deaminations from A->G and C->T occur more on single- than doublestranded DNA. Corresponding replicational nucleotide gradients exist across mito...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Bentham Science Publishers
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269015/ https://www.ncbi.nlm.nih.gov/pubmed/22942674 http://dx.doi.org/10.2174/138920212799034802 |