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Interference Between DNA Replication and Transcription as a Cause of Genomic Instability
Replication and transcription are key aspects of DNA metabolism that take place on the same template and potentially interfere with each other. Conflicts between these two activities include head-on or co-directional collisions between DNA and RNA polymerases, which can lead to the formation of DNA...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Science Publishers
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269018/ https://www.ncbi.nlm.nih.gov/pubmed/22942676 http://dx.doi.org/10.2174/138920212799034767 |