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The Host-Pathogen interaction of human cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains

BACKGROUND: Cyclophilin A (CypA) represents a potential key molecule in future antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication. CypA interacts with the virus proteins Capsid (CA) and Vpr, however, the mechanism through which CypA inf...

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Detalles Bibliográficos
Autores principales:	Solbak, Sara MØ, Wray, Victor, Horvli, Ole, Raae, Arnt J, Flydal, Marte I, Henklein, Petra, Henklein, Peter, Nimtz, Manfred, Schubert, Ulrich, Fossen, Torgils
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269379/ https://www.ncbi.nlm.nih.gov/pubmed/22185200 http://dx.doi.org/10.1186/1472-6807-11-49

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