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Increased GABA(A) Receptor ε-Subunit Expression on Ventral Respiratory Column Neurons Protects Breathing during Pregnancy

GABAergic signaling is essential for proper respiratory function. Potentiation of this signaling with allosteric modulators such as anesthetics, barbiturates, and neurosteroids can lead to respiratory arrest. Paradoxically, pregnant animals continue to breathe normally despite nearly 100-fold increa...

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Detalles Bibliográficos
Autores principales: Hengen, Keith B., Nelson, Nathan R., Stang, Kyle M., Johnson, Stephen M., Crader, Stephanie M., Watters, Jyoti J., Mitchell, Gordon S., Behan, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269439/
https://www.ncbi.nlm.nih.gov/pubmed/22303446
http://dx.doi.org/10.1371/journal.pone.0030608