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Increased GABA(A) Receptor ε-Subunit Expression on Ventral Respiratory Column Neurons Protects Breathing during Pregnancy
GABAergic signaling is essential for proper respiratory function. Potentiation of this signaling with allosteric modulators such as anesthetics, barbiturates, and neurosteroids can lead to respiratory arrest. Paradoxically, pregnant animals continue to breathe normally despite nearly 100-fold increa...
Autores principales: | Hengen, Keith B., Nelson, Nathan R., Stang, Kyle M., Johnson, Stephen M., Crader, Stephanie M., Watters, Jyoti J., Mitchell, Gordon S., Behan, Mary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269439/ https://www.ncbi.nlm.nih.gov/pubmed/22303446 http://dx.doi.org/10.1371/journal.pone.0030608 |
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