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Potentiation of Anticancer Drugs: Effects of Pentoxifylline on Neoplastic Cells

The drug efflux activity of P-glycoprotein (P-gp, a product of the mdr1 gene, ABCB1 member of ABC transporter family) represents a mechanism by which tumor cells escape death induced by chemotherapeutics. In this study, we investigated the mechanisms involved in the effects of pentoxifylline (PTX) o...

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Detalles Bibliográficos
Autores principales: Barancik, Miroslav, Bohacova, Viera, Gibalova, Lenka, Sedlak, Jan, Sulova, Zdena, Breier, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269692/
https://www.ncbi.nlm.nih.gov/pubmed/22312258
http://dx.doi.org/10.3390/ijms13010369