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Potentiation of Anticancer Drugs: Effects of Pentoxifylline on Neoplastic Cells
The drug efflux activity of P-glycoprotein (P-gp, a product of the mdr1 gene, ABCB1 member of ABC transporter family) represents a mechanism by which tumor cells escape death induced by chemotherapeutics. In this study, we investigated the mechanisms involved in the effects of pentoxifylline (PTX) o...
Autores principales: | Barancik, Miroslav, Bohacova, Viera, Gibalova, Lenka, Sedlak, Jan, Sulova, Zdena, Breier, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269692/ https://www.ncbi.nlm.nih.gov/pubmed/22312258 http://dx.doi.org/10.3390/ijms13010369 |
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