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Molecular Modeling Study of Chiral Separation and Recognition Mechanism of β-Adrenergic Antagonists by Capillary Electrophoresis

Chiral separations of five β-adrenergic antagonists (propranolol, esmolol, atenolol, metoprolol, and bisoprolol) were studied by capillary electrophoresis using six cyclodextrins (CDs) as the chiral selectors. Carboxymethylated-β-cyclodextrin (CM-β-CD) exhibited a higher enantioselectivity power com...

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Detalles Bibliográficos
Autores principales: Li, Wuhong, Liu, Changhai, Tan, Guangguo, Zhang, Xinrong, Zhu, Zhenyu, Chai, Yifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269715/
https://www.ncbi.nlm.nih.gov/pubmed/22312281
http://dx.doi.org/10.3390/ijms13010710

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