Photostability of Isovaline and its Precursor 5-Ethyl-5- methylhydantoin Exposed to Simulated Space Radiations

Aqueous solutions of isovaline and its precursor molecule, 5-ethyl-5-methylhydantoin, were irradiated with ultraviolet and γ-ray photons, to evaluate their structural stability against space radiation. The degree of photolysis was measured and irradiation products were identified using chiral, rever...

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Detalles Bibliográficos
Autores principales: Sarker, Palash K., Takahashi, Jun-ichi, Kawamoto, Yukinori, Obayashi, Yumiko, Kaneko, Takeo, Kobayashi, Kensei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269734/
https://www.ncbi.nlm.nih.gov/pubmed/22312300
http://dx.doi.org/10.3390/ijms13011006
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author Sarker, Palash K.
Takahashi, Jun-ichi
Kawamoto, Yukinori
Obayashi, Yumiko
Kaneko, Takeo
Kobayashi, Kensei
author_facet Sarker, Palash K.
Takahashi, Jun-ichi
Kawamoto, Yukinori
Obayashi, Yumiko
Kaneko, Takeo
Kobayashi, Kensei
author_sort Sarker, Palash K.
collection PubMed
description Aqueous solutions of isovaline and its precursor molecule, 5-ethyl-5-methylhydantoin, were irradiated with ultraviolet and γ-ray photons, to evaluate their structural stability against space radiation. The degree of photolysis was measured and irradiation products were identified using chiral, reversed-phase and ion-exchange high-performance liquid chromatography. The experimental results show that the degree of photolysis of 5-ethyl-5-methylhydantoin is more significant than that of isovaline under ultraviolet light irradiation, while the results under γ-ray irradiation are the opposite. As the products of isovaline photolysis, aspartic acid, serine, glutamic acid and alanine were dominantly detected.
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spelling pubmed-32697342012-02-06 Photostability of Isovaline and its Precursor 5-Ethyl-5- methylhydantoin Exposed to Simulated Space Radiations Sarker, Palash K. Takahashi, Jun-ichi Kawamoto, Yukinori Obayashi, Yumiko Kaneko, Takeo Kobayashi, Kensei Int J Mol Sci Article Aqueous solutions of isovaline and its precursor molecule, 5-ethyl-5-methylhydantoin, were irradiated with ultraviolet and γ-ray photons, to evaluate their structural stability against space radiation. The degree of photolysis was measured and irradiation products were identified using chiral, reversed-phase and ion-exchange high-performance liquid chromatography. The experimental results show that the degree of photolysis of 5-ethyl-5-methylhydantoin is more significant than that of isovaline under ultraviolet light irradiation, while the results under γ-ray irradiation are the opposite. As the products of isovaline photolysis, aspartic acid, serine, glutamic acid and alanine were dominantly detected. Molecular Diversity Preservation International (MDPI) 2012-01-17 /pmc/articles/PMC3269734/ /pubmed/22312300 http://dx.doi.org/10.3390/ijms13011006 Text en © 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Sarker, Palash K.
Takahashi, Jun-ichi
Kawamoto, Yukinori
Obayashi, Yumiko
Kaneko, Takeo
Kobayashi, Kensei
Photostability of Isovaline and its Precursor 5-Ethyl-5- methylhydantoin Exposed to Simulated Space Radiations
title Photostability of Isovaline and its Precursor 5-Ethyl-5- methylhydantoin Exposed to Simulated Space Radiations
title_full Photostability of Isovaline and its Precursor 5-Ethyl-5- methylhydantoin Exposed to Simulated Space Radiations
title_fullStr Photostability of Isovaline and its Precursor 5-Ethyl-5- methylhydantoin Exposed to Simulated Space Radiations
title_full_unstemmed Photostability of Isovaline and its Precursor 5-Ethyl-5- methylhydantoin Exposed to Simulated Space Radiations
title_short Photostability of Isovaline and its Precursor 5-Ethyl-5- methylhydantoin Exposed to Simulated Space Radiations
title_sort photostability of isovaline and its precursor 5-ethyl-5- methylhydantoin exposed to simulated space radiations
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269734/
https://www.ncbi.nlm.nih.gov/pubmed/22312300
http://dx.doi.org/10.3390/ijms13011006
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