Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors

Childhood cancer is the leading cause of death by disease among U.S. children between infancy and age 15. Despite successes in treating solid tumors such as Wilms tumor, disappointments in the outcomes of high-risk solid tumors like neuroblastoma have precipitated efforts towards the early and accur...

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Detalles Bibliográficos
Autores principales: Sandoval, John A., Malkas, Linda H., Hickey, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269742/
https://www.ncbi.nlm.nih.gov/pubmed/22312308
http://dx.doi.org/10.3390/ijms13011126
Descripción
Sumario:Childhood cancer is the leading cause of death by disease among U.S. children between infancy and age 15. Despite successes in treating solid tumors such as Wilms tumor, disappointments in the outcomes of high-risk solid tumors like neuroblastoma have precipitated efforts towards the early and accurate detection of these malignancies. This review summarizes available solid tumor serum biomarkers with a special focus on mediastinal and abdominal cancers in children.

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