Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors

Childhood cancer is the leading cause of death by disease among U.S. children between infancy and age 15. Despite successes in treating solid tumors such as Wilms tumor, disappointments in the outcomes of high-risk solid tumors like neuroblastoma have precipitated efforts towards the early and accur...

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Detalles Bibliográficos
Autores principales: Sandoval, John A., Malkas, Linda H., Hickey, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269742/
https://www.ncbi.nlm.nih.gov/pubmed/22312308
http://dx.doi.org/10.3390/ijms13011126
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author Sandoval, John A.
Malkas, Linda H.
Hickey, Robert J.
author_facet Sandoval, John A.
Malkas, Linda H.
Hickey, Robert J.
author_sort Sandoval, John A.
collection PubMed
description Childhood cancer is the leading cause of death by disease among U.S. children between infancy and age 15. Despite successes in treating solid tumors such as Wilms tumor, disappointments in the outcomes of high-risk solid tumors like neuroblastoma have precipitated efforts towards the early and accurate detection of these malignancies. This review summarizes available solid tumor serum biomarkers with a special focus on mediastinal and abdominal cancers in children.
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spelling pubmed-32697422012-02-06 Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors Sandoval, John A. Malkas, Linda H. Hickey, Robert J. Int J Mol Sci Review Childhood cancer is the leading cause of death by disease among U.S. children between infancy and age 15. Despite successes in treating solid tumors such as Wilms tumor, disappointments in the outcomes of high-risk solid tumors like neuroblastoma have precipitated efforts towards the early and accurate detection of these malignancies. This review summarizes available solid tumor serum biomarkers with a special focus on mediastinal and abdominal cancers in children. Molecular Diversity Preservation International (MDPI) 2012-01-20 /pmc/articles/PMC3269742/ /pubmed/22312308 http://dx.doi.org/10.3390/ijms13011126 Text en © 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Review
Sandoval, John A.
Malkas, Linda H.
Hickey, Robert J.
Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors
title Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors
title_full Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors
title_fullStr Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors
title_full_unstemmed Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors
title_short Clinical Significance of Serum Biomarkers in Pediatric Solid Mediastinal and Abdominal Tumors
title_sort clinical significance of serum biomarkers in pediatric solid mediastinal and abdominal tumors
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269742/
https://www.ncbi.nlm.nih.gov/pubmed/22312308
http://dx.doi.org/10.3390/ijms13011126
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