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Inhibition of AKT2 Enhances Sensitivity to Gemcitabine via Regulating PUMA and NF-κB Signaling Pathway in Human Pancreatic Ductal Adenocarcinoma
Invasion, metastasis and resistance to conventional chemotherapeutic agents are obstacles to successful treatment of pancreatic cancer, and a better understanding of the molecular basis of this malignancy may lead to improved therapeutics. In the present study, we investigated whether AKT2 silencing...
Autores principales: | Chen, Dong, Niu, Min, Jiao, Xuelong, Zhang, Kejun, Liang, Jun, Zhang, Dianliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269746/ https://www.ncbi.nlm.nih.gov/pubmed/22312312 http://dx.doi.org/10.3390/ijms13011186 |
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