Cargando…
Disruption of Axonal Transport in Motor Neuron Diseases
Motor neurons typically have very long axons, and fine-tuning axonal transport is crucial for their survival. The obstruction of axonal transport is gaining attention as a cause of neuronal dysfunction in a variety of neurodegenerative motor neuron diseases. Depletions in dynein and dynactin-1, moto...
Autores principales: | Ikenaka, Kensuke, Katsuno, Masahisa, Kawai, Kaori, Ishigaki, Shinsuke, Tanaka, Fumiaki, Sobue, Gen |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International (MDPI)
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269748/ https://www.ncbi.nlm.nih.gov/pubmed/22312314 http://dx.doi.org/10.3390/ijms13011225 |
Ejemplares similares
-
dnc-1/dynactin 1 Knockdown Disrupts Transport of Autophagosomes and Induces Motor Neuron Degeneration
por: Ikenaka, Kensuke, et al.
Publicado: (2013) -
c-Abl Inhibition Delays Motor Neuron Degeneration in the G93A Mouse, an Animal Model of Amyotrophic Lateral Sclerosis
por: Katsumata, Ryu, et al.
Publicado: (2012) -
A behavior-based drug screening system using a Caenorhabditis elegans model of motor neuron disease
por: Ikenaka, Kensuke, et al.
Publicado: (2019) -
RNP2 of RNA Recognition Motif 1 Plays a Central Role in the Aberrant Modification of TDP-43
por: Takagi, Shinnosuke, et al.
Publicado: (2013) -
TDP-43 Proteinopathy and Tauopathy: Do They Have Pathomechanistic Links?
por: Riku, Yuichi, et al.
Publicado: (2022)