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Aspiration pneumonia and death in Huntington’s disease
Huntington’s disease (HD) is a progressive neurodegenerative autosomal dominant disease characterized by choreatic and hypokinetic movements, disturbed behaviour, and cognitive decline. Pneumonia is the most common cause of death, followed by cardiovasculair diseases. It has been suggested that chok...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269785/ https://www.ncbi.nlm.nih.gov/pubmed/22307361 http://dx.doi.org/10.1371/currents.RRN1293 |
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author | Heemskerk, Anne-Wil Roos, Raymund A.C. |
author_facet | Heemskerk, Anne-Wil Roos, Raymund A.C. |
author_sort | Heemskerk, Anne-Wil |
collection | PubMed |
description | Huntington’s disease (HD) is a progressive neurodegenerative autosomal dominant disease characterized by choreatic and hypokinetic movements, disturbed behaviour, and cognitive decline. Pneumonia is the most common cause of death, followed by cardiovasculair diseases. It has been suggested that choking is the causative underlying factor for pneumonia in HD. As a detailed specification of the type of pneumonia has never been performed, we analyzed the records of our Brain Bank containing 224 cases to determine the exact cause of death and type of pneumonia. The conclusion is that the majority (86.8%) of our HD patients where the cause of death could be identified died from aspiration pneumonia. |
format | Online Article Text |
id | pubmed-3269785 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-32697852012-02-02 Aspiration pneumonia and death in Huntington’s disease Heemskerk, Anne-Wil Roos, Raymund A.C. PLoS Curr Huntington Disease Huntington’s disease (HD) is a progressive neurodegenerative autosomal dominant disease characterized by choreatic and hypokinetic movements, disturbed behaviour, and cognitive decline. Pneumonia is the most common cause of death, followed by cardiovasculair diseases. It has been suggested that choking is the causative underlying factor for pneumonia in HD. As a detailed specification of the type of pneumonia has never been performed, we analyzed the records of our Brain Bank containing 224 cases to determine the exact cause of death and type of pneumonia. The conclusion is that the majority (86.8%) of our HD patients where the cause of death could be identified died from aspiration pneumonia. Public Library of Science 2012-02-02 /pmc/articles/PMC3269785/ /pubmed/22307361 http://dx.doi.org/10.1371/currents.RRN1293 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Huntington Disease Heemskerk, Anne-Wil Roos, Raymund A.C. Aspiration pneumonia and death in Huntington’s disease |
title | Aspiration pneumonia and death in Huntington’s disease |
title_full | Aspiration pneumonia and death in Huntington’s disease |
title_fullStr | Aspiration pneumonia and death in Huntington’s disease |
title_full_unstemmed | Aspiration pneumonia and death in Huntington’s disease |
title_short | Aspiration pneumonia and death in Huntington’s disease |
title_sort | aspiration pneumonia and death in huntington’s disease |
topic | Huntington Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269785/ https://www.ncbi.nlm.nih.gov/pubmed/22307361 http://dx.doi.org/10.1371/currents.RRN1293 |
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