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Genotype-informed estimation of risk of coronary heart disease based on genome-wide association data linked to the electronic medical record

BACKGROUND: Susceptibility variants identified by genome-wide association studies (GWAS) have modest effect sizes. Whether such variants provide incremental information in assessing risk for common 'complex' diseases is unclear. We investigated whether measured and imputed genotypes from a...

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Detalles Bibliográficos
Autores principales:	Ding, Keyue, Bailey, Kent R, Kullo, Iftikhar J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269823/ https://www.ncbi.nlm.nih.gov/pubmed/22151179 http://dx.doi.org/10.1186/1471-2261-11-66

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