Association of COMT genotypes with S-COMT promoter methylation in growth-discordant monozygotic twins and healthy adults

BACKGROUND: Catechol-O-Methyltransferase (COMT) plays a key role in dopamine and estrogen metabolism. Recently, COMT haplotypes rather than the single polymorphism Val158Met have been reported to underlie differences in protein expression by modulating mRNA secondary structure. So far, studies inves...

Descripción completa

Detalles Bibliográficos
Autores principales: Schreiner, Felix, El-Maarri, Osman, Gohlke, Bettina, Stutte, Sonja, Nuesgen, Nicole, Mattheisen, Manuel, Fimmers, Rolf, Bartmann, Peter, Oldenburg, Johannes, Woelfle, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270002/
https://www.ncbi.nlm.nih.gov/pubmed/21884617
http://dx.doi.org/10.1186/1471-2350-12-115

Ejemplares similares

Ejemplares similares