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Regrowing the Adult Brain: NF-κB Controls Functional Circuit Formation and Tissue Homeostasis in the Dentate Gyrus
Cognitive decline during aging is correlated with a continuous loss of cells within the brain and especially within the hippocampus, which could be regenerated by adult neurogenesis. Here we show that genetic ablation of NF-κB resulted in severe defects in the neurogenic region (dentate gyrus) of th...
Autores principales: | Imielski, Yvonne, Schwamborn, Jens C., Lüningschrör, Patrick, Heimann, Peter, Holzberg, Magdalena, Werner, Hendrikje, Leske, Oliver, Püschel, Andreas W., Memet, Sylvie, Heumann, Rolf, Israel, Alain, Kaltschmidt, Christian, Kaltschmidt, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270021/ https://www.ncbi.nlm.nih.gov/pubmed/22312433 http://dx.doi.org/10.1371/journal.pone.0030838 |
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