Coronavirus Papain-like Proteases Negatively Regulate Antiviral Innate Immune Response through Disruption of STING-Mediated Signaling

Viruses have evolved elaborate mechanisms to evade or inactivate the complex system of sensors and signaling molecules that make up the host innate immune response. Here we show that human coronavirus (HCoV) NL63 and severe acute respiratory syndrome (SARS) CoV papain-like proteases (PLP) antagonize...

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Detalles Bibliográficos
Autores principales: Sun, Li, Xing, Yaling, Chen, Xiaojuan, Zheng, Yang, Yang, Yudong, Nichols, Daniel B., Clementz, Mark A., Banach, Bridget S., Li, Kui, Baker, Susan C., Chen, Zhongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270028/
https://www.ncbi.nlm.nih.gov/pubmed/22312431
http://dx.doi.org/10.1371/journal.pone.0030802

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