Deep Amino Acid Sequencing of Native Brain GABA(A) Receptors Using High-Resolution Mass Spectrometry

Mass spectrometric sequencing of low abundance, integral membrane proteins, particularly the transmembrane domains, presents challenges that span the multiple phases of sample preparation including solubilization, purification, enzymatic digestion, peptide extraction, and chromatographic separation....

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Detalles Bibliográficos
Autores principales: Chen, Zi-Wei, Fuchs, Karoline, Sieghart, Werner, Townsend, R. Reid, Evers, Alex S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270104/
https://www.ncbi.nlm.nih.gov/pubmed/22338125
http://dx.doi.org/10.1074/mcp.M111.011445

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