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Elevated calpain activity in acute myelogenous leukemia correlates with decreased calpastatin expression
Calpains are intracellular cysteine proteases that have crucial roles in many physiological and pathological processes. Elevated calpain activity has been associated with many pathological states. Calpain inhibition can be protective or lethal depending on the context. Previous work has shown that c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270254/ https://www.ncbi.nlm.nih.gov/pubmed/22829235 http://dx.doi.org/10.1038/bcj.2011.50 |