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Elevated calpain activity in acute myelogenous leukemia correlates with decreased calpastatin expression

Calpains are intracellular cysteine proteases that have crucial roles in many physiological and pathological processes. Elevated calpain activity has been associated with many pathological states. Calpain inhibition can be protective or lethal depending on the context. Previous work has shown that c...

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Detalles Bibliográficos
Autores principales: Niapour, M, Farr, C, Minden, M, Berger, S A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270254/
https://www.ncbi.nlm.nih.gov/pubmed/22829235
http://dx.doi.org/10.1038/bcj.2011.50