ER stress activates the NLRP3 inflammasome via an UPR-independent pathway

Uncontrolled endoplasmic reticulum (ER) stress responses are proposed to contribute to the pathology of chronic inflammatory diseases such as type 2 diabetes or atherosclerosis. However, the connection between ER stress and inflammation remains largely unexplored. Here, we show that ER stress causes...

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Detalles Bibliográficos
Autores principales: Menu, P, Mayor, A, Zhou, R, Tardivel, A, Ichijo, H, Mori, K, Tschopp, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270266/
https://www.ncbi.nlm.nih.gov/pubmed/22278288
http://dx.doi.org/10.1038/cddis.2011.132

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