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Stem cell gene expression in MRPS18-2-immortalized rat embryonic fibroblasts

We have recently found that primary rat embryonic fibroblasts (REFs) could be immortalized by overexpression of the human mitochondrial ribosomal protein MRPS18-2 (S18-2). A derived cell line, designated 18IM, expressed the embryonic stem cell markers SSEA-1 and Sox2. Upon inoculation into severe co...

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Detalles Bibliográficos
Autores principales: Yenamandra, S P, Darekar, S D, Kashuba, V, Matskova, L, Klein, G, Kashuba, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270272/
https://www.ncbi.nlm.nih.gov/pubmed/22258410
http://dx.doi.org/10.1038/cddis.2011.138