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Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells

Taxanes remain first line chemotherapy in management of metastatic breast cancer and have a key role in epithelial ovarian cancer, with increasingly common use of weekly paclitaxel dosing regimens. However, their clinical utility is limited by the development of chemoresistance. To address this, we...

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Detalles Bibliográficos
Autores principales: Ajabnoor, G M A, Crook, T, Coley, H M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270273/
https://www.ncbi.nlm.nih.gov/pubmed/22278287
http://dx.doi.org/10.1038/cddis.2011.139