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Altered dynamics of ubiquitin hybrid proteins during tumor cell apoptosis

The ubiquitin hybrid genes Uba80 and Uba52 encode ubiquitin (Ub), which is fused to the ribosomal proteins S27a (RPS27a) and L40 (RPL40), respectively. Here, we show that these genes are preferentially over-expressed during hepatoma cell apoptosis. Experiments using the tet-inducible transgenic syst...

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Detalles Bibliográficos
Autores principales: Han, X-J, Lee, M-J, Yu, G-R, Lee, Z-W, Bae, J-Y, Bae, Y-C, Kang, S-H, Kim, D-G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270276/
https://www.ncbi.nlm.nih.gov/pubmed/22258406
http://dx.doi.org/10.1038/cddis.2011.142