Imbalance of neurotrophin receptor isoforms TrkB-FL/TrkB-T1 induces neuronal death in excitotoxicity

A better understanding of the mechanisms underlying neuronal death in cerebral ischemia is required for the development of stroke therapies. Here we analyze the contribution of the tropomyosin-related kinase B (TrkB) neurotrophin receptor to excitotoxicity, a primary pathological mechanism in ischem...

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Detalles Bibliográficos
Autores principales: Vidaurre, Ó G, Gascón, S, Deogracias, R, Sobrado, M, Cuadrado, E, Montaner, J, Rodríguez-Peña, Á, Díaz-Guerra, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270277/
https://www.ncbi.nlm.nih.gov/pubmed/22258407
http://dx.doi.org/10.1038/cddis.2011.143

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