Cargando…
Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children
The aim of this study was to investigate the independent associations among cardiorespiratory fitness, metabolic syndrome (MetS), and C-reactive protein (CRP) in children. The sample consisted of 112 children (11.4 ± 0.4 years). Data was obtained for children's anthropometry, cardiorespirator...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270402/ https://www.ncbi.nlm.nih.gov/pubmed/22315623 http://dx.doi.org/10.1155/2012/270515 |
_version_ | 1782222571095195648 |
---|---|
author | Christodoulos, Antonios D. Douda, Helen T. Tokmakidis, Savvas P. |
author_facet | Christodoulos, Antonios D. Douda, Helen T. Tokmakidis, Savvas P. |
author_sort | Christodoulos, Antonios D. |
collection | PubMed |
description | The aim of this study was to investigate the independent associations among cardiorespiratory fitness, metabolic syndrome (MetS), and C-reactive protein (CRP) in children. The sample consisted of 112 children (11.4 ± 0.4 years). Data was obtained for children's anthropometry, cardiorespiratory fitness, MetS components, and CRP levels. MetS was defined using criteria analogous to the Adult Treatment Panel III definition. A MetS risk score was also computed. Prevalence of the MetS was 5.4%, without gender differences. Subjects with low fitness showed significantly higher MetS risk (P < 0.001) and CRP (P < 0.007), compared to the high-fitness pupils. However, differences in MetS risk, and CRP between fitness groups decreased when adjusted for waist circumference. These data indicate that the mechanisms linking cardiorespiratory fitness, MetS risk and inflammation in children are extensively affected by obesity. Intervention strategies aiming at reducing obesity and improving cardiorespiratory fitness in childhood might contribute to the prevention of the MetS in adulthood. |
format | Online Article Text |
id | pubmed-3270402 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-32704022012-02-07 Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children Christodoulos, Antonios D. Douda, Helen T. Tokmakidis, Savvas P. Int J Pediatr Clinical Study The aim of this study was to investigate the independent associations among cardiorespiratory fitness, metabolic syndrome (MetS), and C-reactive protein (CRP) in children. The sample consisted of 112 children (11.4 ± 0.4 years). Data was obtained for children's anthropometry, cardiorespiratory fitness, MetS components, and CRP levels. MetS was defined using criteria analogous to the Adult Treatment Panel III definition. A MetS risk score was also computed. Prevalence of the MetS was 5.4%, without gender differences. Subjects with low fitness showed significantly higher MetS risk (P < 0.001) and CRP (P < 0.007), compared to the high-fitness pupils. However, differences in MetS risk, and CRP between fitness groups decreased when adjusted for waist circumference. These data indicate that the mechanisms linking cardiorespiratory fitness, MetS risk and inflammation in children are extensively affected by obesity. Intervention strategies aiming at reducing obesity and improving cardiorespiratory fitness in childhood might contribute to the prevention of the MetS in adulthood. Hindawi Publishing Corporation 2012 2012-01-24 /pmc/articles/PMC3270402/ /pubmed/22315623 http://dx.doi.org/10.1155/2012/270515 Text en Copyright © 2012 Antonios D. Christodoulos et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Clinical Study Christodoulos, Antonios D. Douda, Helen T. Tokmakidis, Savvas P. Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children |
title | Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children |
title_full | Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children |
title_fullStr | Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children |
title_full_unstemmed | Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children |
title_short | Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children |
title_sort | cardiorespiratory fitness, metabolic risk, and inflammation in children |
topic | Clinical Study |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270402/ https://www.ncbi.nlm.nih.gov/pubmed/22315623 http://dx.doi.org/10.1155/2012/270515 |
work_keys_str_mv | AT christodoulosantoniosd cardiorespiratoryfitnessmetabolicriskandinflammationinchildren AT doudahelent cardiorespiratoryfitnessmetabolicriskandinflammationinchildren AT tokmakidissavvasp cardiorespiratoryfitnessmetabolicriskandinflammationinchildren |