Cargando…

Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children

The aim of this study was to investigate the independent associations among cardiorespiratory fitness, metabolic syndrome (MetS), and C-reactive protein (CRP) in children. The sample consisted of 112 children (11.4  ±  0.4 years). Data was obtained for children's anthropometry, cardiorespirator...

Descripción completa

Detalles Bibliográficos
Autores principales: Christodoulos, Antonios D., Douda, Helen T., Tokmakidis, Savvas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270402/
https://www.ncbi.nlm.nih.gov/pubmed/22315623
http://dx.doi.org/10.1155/2012/270515
_version_ 1782222571095195648
author Christodoulos, Antonios D.
Douda, Helen T.
Tokmakidis, Savvas P.
author_facet Christodoulos, Antonios D.
Douda, Helen T.
Tokmakidis, Savvas P.
author_sort Christodoulos, Antonios D.
collection PubMed
description The aim of this study was to investigate the independent associations among cardiorespiratory fitness, metabolic syndrome (MetS), and C-reactive protein (CRP) in children. The sample consisted of 112 children (11.4  ±  0.4 years). Data was obtained for children's anthropometry, cardiorespiratory fitness, MetS components, and CRP levels. MetS was defined using criteria analogous to the Adult Treatment Panel III definition. A MetS risk score was also computed. Prevalence of the MetS was 5.4%, without gender differences. Subjects with low fitness showed significantly higher MetS risk (P < 0.001) and CRP (P < 0.007), compared to the high-fitness pupils. However, differences in MetS risk, and CRP between fitness groups decreased when adjusted for waist circumference. These data indicate that the mechanisms linking cardiorespiratory fitness, MetS risk and inflammation in children are extensively affected by obesity. Intervention strategies aiming at reducing obesity and improving cardiorespiratory fitness in childhood might contribute to the prevention of the MetS in adulthood.
format Online
Article
Text
id pubmed-3270402
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-32704022012-02-07 Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children Christodoulos, Antonios D. Douda, Helen T. Tokmakidis, Savvas P. Int J Pediatr Clinical Study The aim of this study was to investigate the independent associations among cardiorespiratory fitness, metabolic syndrome (MetS), and C-reactive protein (CRP) in children. The sample consisted of 112 children (11.4  ±  0.4 years). Data was obtained for children's anthropometry, cardiorespiratory fitness, MetS components, and CRP levels. MetS was defined using criteria analogous to the Adult Treatment Panel III definition. A MetS risk score was also computed. Prevalence of the MetS was 5.4%, without gender differences. Subjects with low fitness showed significantly higher MetS risk (P < 0.001) and CRP (P < 0.007), compared to the high-fitness pupils. However, differences in MetS risk, and CRP between fitness groups decreased when adjusted for waist circumference. These data indicate that the mechanisms linking cardiorespiratory fitness, MetS risk and inflammation in children are extensively affected by obesity. Intervention strategies aiming at reducing obesity and improving cardiorespiratory fitness in childhood might contribute to the prevention of the MetS in adulthood. Hindawi Publishing Corporation 2012 2012-01-24 /pmc/articles/PMC3270402/ /pubmed/22315623 http://dx.doi.org/10.1155/2012/270515 Text en Copyright © 2012 Antonios D. Christodoulos et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Christodoulos, Antonios D.
Douda, Helen T.
Tokmakidis, Savvas P.
Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children
title Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children
title_full Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children
title_fullStr Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children
title_full_unstemmed Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children
title_short Cardiorespiratory Fitness, Metabolic Risk, and Inflammation in Children
title_sort cardiorespiratory fitness, metabolic risk, and inflammation in children
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270402/
https://www.ncbi.nlm.nih.gov/pubmed/22315623
http://dx.doi.org/10.1155/2012/270515
work_keys_str_mv AT christodoulosantoniosd cardiorespiratoryfitnessmetabolicriskandinflammationinchildren
AT doudahelent cardiorespiratoryfitnessmetabolicriskandinflammationinchildren
AT tokmakidissavvasp cardiorespiratoryfitnessmetabolicriskandinflammationinchildren