Bayesian Analysis of a Lipid-Based Physiologically Based Toxicokinetic Model for a Mixture of PCBs in Rats

A lipid-based physiologically based toxicokinetic (PBTK) model has been developed for a mixture of six polychlorinated biphenyls (PCBs) in rats. The aim of this study was to apply population Bayesian analysis to a lipid PBTK model, while incorporating an internal exposure-response model linking enzy...

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Detalles Bibliográficos
Autores principales: Sasso, Alan F., Georgopoulos, Panos G., Isukapalli, Sastry S., Krishnan, Kannan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270437/
https://www.ncbi.nlm.nih.gov/pubmed/22315591
http://dx.doi.org/10.1155/2012/895391

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270437/
https://www.ncbi.nlm.nih.gov/pubmed/22315591
http://dx.doi.org/10.1155/2012/895391

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