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Deoxyribonuclease Is a Potential Counter Regulator of Aberrant Neutrophil Extracellular Traps Formation after Major Trauma

Introduction. Neutrophil extracellular traps (NET) consist of a DNA scaffold that can be destroyed by Deoxyribonuclease (DNase). Thus DNases are potential prerequisites for natural counter regulation of NETs formation. In the present study, we determined the relationship of NETs and DNase after majo...

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Detalles Bibliográficos
Autores principales: Meng, Wei, Paunel-Görgülü, Adnana, Flohé, Sascha, Witte, Ingo, Schädel-Höpfner, Michael, Windolf, Joachim, Lögters, Tim Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270459/
https://www.ncbi.nlm.nih.gov/pubmed/22315507
http://dx.doi.org/10.1155/2012/149560