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Lipids as conductors in the orchestra of life
The lipid phosphatidic acid is an important metabolic intermediate in the biosynthesis of lipids in all eukaryotic cells, but it is even more than that. Phosphatidic acid is emerging as a lipid that is both composer and conductor, where in addition to its role as biosynthetic precursor (composer) it...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Faculty of 1000 Ltd
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270589/ https://www.ncbi.nlm.nih.gov/pubmed/22312416 http://dx.doi.org/10.3410/B4-4 |
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| author | Loewen, Christopher J.R. |
| author_facet | Loewen, Christopher J.R. |
| author_sort | Loewen, Christopher J.R. |
| collection | PubMed |
| description | The lipid phosphatidic acid is an important metabolic intermediate in the biosynthesis of lipids in all eukaryotic cells, but it is even more than that. Phosphatidic acid is emerging as a lipid that is both composer and conductor, where in addition to its role as biosynthetic precursor (composer) it is also a potent signaling molecule (conductor) that integrates membrane biogenesis with nutrient sensing and cell growth. This article discusses recent advances in yeast that give praise for phosphatidic acid as one of life's conductors. |
| format | Online Article Text |
| id | pubmed-3270589 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2012 |
| publisher | Faculty of 1000 Ltd |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-32705892012-02-06 Lipids as conductors in the orchestra of life Loewen, Christopher J.R. F1000 Biol Rep Review Article The lipid phosphatidic acid is an important metabolic intermediate in the biosynthesis of lipids in all eukaryotic cells, but it is even more than that. Phosphatidic acid is emerging as a lipid that is both composer and conductor, where in addition to its role as biosynthetic precursor (composer) it is also a potent signaling molecule (conductor) that integrates membrane biogenesis with nutrient sensing and cell growth. This article discusses recent advances in yeast that give praise for phosphatidic acid as one of life's conductors. Faculty of 1000 Ltd 2012-02-01 /pmc/articles/PMC3270589/ /pubmed/22312416 http://dx.doi.org/10.3410/B4-4 Text en © 2012 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. You may not use this work for commercial purposes |
| spellingShingle | Review Article Loewen, Christopher J.R. Lipids as conductors in the orchestra of life |
| title | Lipids as conductors in the orchestra of life |
| title_full | Lipids as conductors in the orchestra of life |
| title_fullStr | Lipids as conductors in the orchestra of life |
| title_full_unstemmed | Lipids as conductors in the orchestra of life |
| title_short | Lipids as conductors in the orchestra of life |
| title_sort | lipids as conductors in the orchestra of life |
| topic | Review Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3270589/ https://www.ncbi.nlm.nih.gov/pubmed/22312416 http://dx.doi.org/10.3410/B4-4 |
| work_keys_str_mv | AT loewenchristopherjr lipidsasconductorsintheorchestraoflife |