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Accumulation of CCR4(+) CTLA-4(hi) FOXP3(+)CD25(hi) Regulatory T Cells in Colon Adenocarcinomas Correlate to Reduced Activation of Conventional T Cells
BACKGROUND: Colorectal cancer usually gives rise to a specific anti-tumor immune response, but for unknown reasons the resulting immunity is not able to clear the tumor. Recruitment of activated effector lymphocytes to the tumor is important for efficient anti-tumor responses, while the presence of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271060/ https://www.ncbi.nlm.nih.gov/pubmed/22319577 http://dx.doi.org/10.1371/journal.pone.0030695 |