Raf1 Is a DCAF for the Rik1 DDB1-Like Protein and Has Separable Roles in siRNA Generation and Chromatin Modification

Non-coding transcription can trigger histone post-translational modifications forming specialized chromatin. In fission yeast, heterochromatin formation requires RNAi and the histone H3K9 methyltransferase complex CLRC, composed of Clr4, Raf1, Raf2, Cul4, and Rik1. CLRC mediates H3K9 methylation and...

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Detalles Bibliográficos
Autores principales: Buscaino, Alessia, White, Sharon A., Houston, Douglas R., Lejeune, Erwan, Simmer, Femke, de Lima Alves, Flavia, Diyora, Piyush T., Urano, Takeshi, Bayne, Elizabeth H., Rappsilber, Juri, Allshire, Robin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271066/
https://www.ncbi.nlm.nih.gov/pubmed/22319459
http://dx.doi.org/10.1371/journal.pgen.1002499

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