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Sequence Heterogeneity in NS5A of Hepatitis C Virus Genotypes 2a and 2b and Clinical Outcome of Pegylated-Interferon/Ribavirin Therapy

Pegylated-interferon plus ribavirin (PEG-IFN/RBV) therapy is a current standard treatment for chronic hepatitis C. We previously reported that the viral sequence heterogeneity of part of NS5A, referred to as the IFN/RBV resistance-determining region (IRRDR), and a mutation at position 70 of the core...

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Detalles Bibliográficos
Autores principales:	El-Shamy, Ahmed, Shoji, Ikuo, Kim, Soo-Ryang, Ide, Yoshihiro, Imoto, Susumu, Deng, Lin, Yoon, Seitetsu, Fujisawa, Takashi, Tani, Satoshi, Yano, Yoshihiko, Seo, Yasushi, Azuma, Takeshi, Hotta, Hak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271109/ https://www.ncbi.nlm.nih.gov/pubmed/22319571 http://dx.doi.org/10.1371/journal.pone.0030513

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