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Proteomic Consequences of a Single Gene Mutation in a Colorectal Cancer Model

[Image: see text] The proteomic effects of specific cancer-related mutations have not been well characterized. In colorectal cancer (CRC), a relatively small number of mutations in key signaling pathways appear to drive tumorigenesis. Mutations in adenomatous polyposis coli (APC), a negative regulat...

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Detalles Bibliográficos
Autores principales: Halvey, Patrick J., Zhang, Bing, Coffey, Robert J., Liebler, Daniel C., Slebos, Robbert J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2011
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271737/
https://www.ncbi.nlm.nih.gov/pubmed/22103262
http://dx.doi.org/10.1021/pr2009109