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A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness

BACKGROUND: The pathophysiology of asthma involves allergic inflammation and remodelling in the airway and airway hyperresponsiveness (AHR) to cholinergic stimuli, but many details of the specific underlying cellular and molecular mechanisms remain unknown. Periostin is a matricellular protein with...

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Detalles Bibliográficos
Autores principales:	Gordon, E D, Sidhu, S S, Wang, Z-E, Woodruff, P G, Yuan, S, Solon, M C, Conway, S J, Huang, X, Locksley, R M, Fahy, J V
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2012
Materias:	Original Articles: Editor's Choice: Experimental Models of Allergic Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271792/ https://www.ncbi.nlm.nih.gov/pubmed/22093101 http://dx.doi.org/10.1111/j.1365-2222.2011.03840.x

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