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A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyperresponsiveness
BACKGROUND: The pathophysiology of asthma involves allergic inflammation and remodelling in the airway and airway hyperresponsiveness (AHR) to cholinergic stimuli, but many details of the specific underlying cellular and molecular mechanisms remain unknown. Periostin is a matricellular protein with...
Autores principales: | Gordon, E D, Sidhu, S S, Wang, Z-E, Woodruff, P G, Yuan, S, Solon, M C, Conway, S J, Huang, X, Locksley, R M, Fahy, J V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271792/ https://www.ncbi.nlm.nih.gov/pubmed/22093101 http://dx.doi.org/10.1111/j.1365-2222.2011.03840.x |
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