Cargando…

Systemic administration of urocortin after intracerebral hemorrhage reduces neurological deficits and neuroinflammation in rats

BACKGROUND: Intracerebral hemorrhage (ICH) remains a serious clinical problem lacking effective treatment. Urocortin (UCN), a novel anti-inflammatory neuropeptide, protects injured cardiomyocytes and dopaminergic neurons. Our preliminary studies indicate UCN alleviates ICH-induced brain injury when...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liew, Hock-Kean, Pang, Cheng-Yoong, Hsu, Chih-Wei, Wang, Mei-Jen, Li, Ting-Yi, Peng, Hsiao-Fen, Kuo, Jon-Son, Wang, Jia-Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271957/ https://www.ncbi.nlm.nih.gov/pubmed/22257737 http://dx.doi.org/10.1186/1742-2094-9-13

Ejemplares similares

The Role of Urocortins in Intracerebral Hemorrhage
por: Choy, Ker Woon, et al.
Publicado: (2020)

Delayed formation of hematomas with ethanol preconditioning in experimental intracerebral hemorrhage rats
por: Cheng, Hung-Yu, et al.
Publicado: (2018)

Over-Activated Proteasome Mediates Neuroinflammation on Acute Intracerebral Hemorrhage in Rats
por: Liew, Hock-Kean, et al.
Publicado: (2019)

A Role for Endoplasmic Reticulum Stress in Intracerebral Hemorrhage
por: Mohammed Thangameeran, Shaik Ismail, et al.
Publicado: (2020)

Resveratrol attenuates neurological deficit and neuroinflammation following intracerebral hemorrhage
por: Cai, Jia-Chen, et al.
Publicado: (2018)

Experimental animal models and evaluation techniques in intracerebral hemorrhage
por: Thangameeran, Shaik Ismail Mohammed, et al.
Publicado: (2022)

Granulocyte-Colony Stimulating Factor Increases Cerebral Blood Flow via a NO Surge Mediated by Akt/eNOS Pathway to Reduce Ischemic Injury
por: Liew, Hock-Kean, et al.
Publicado: (2015)

Rosuvastatin Nanomicelles Target Neuroinflammation and Improve Neurological Deficit in a Mouse Model of Intracerebral Hemorrhage
por: Zi, Liu, et al.
Publicado: (2021)

Human adipose-derived stem cells for the treatment of intracerebral hemorrhage in rats via femoral intravenous injection
por: Yang, Kuo-Liang, et al.
Publicado: (2012)

Neuroinflammation after intracerebral hemorrhage
por: Mracsko, Eva, et al.
Publicado: (2014)

Glibenclamide Attenuates Neuroinflammation and Promotes Neurological Recovery After Intracerebral Hemorrhage in Aged Rats
por: Jiang, Bing, et al.
Publicado: (2021)

Dental Pulp Stem Cell-Derived Factors Alleviate Subarachnoid Hemorrhage-Induced Neuroinflammation and Ischemic Neurological Deficits
por: Chen, Te-Fu, et al.
Publicado: (2019)

Augmenting hematoma-scavenging capacity of innate immune cells by CDNF reduces brain injury and promotes functional recovery after intracerebral hemorrhage
por: Tseng, Kuan-Yin, et al.
Publicado: (2023)

Characterization of Axon Damage, Neurological Deficits, and Histopathology in Two Experimental Models of Intracerebral Hemorrhage
por: Liu, Yao, et al.
Publicado: (2018)

Intranasal Delivery of Gene-Edited Microglial Exosomes Improves Neurological Outcomes after Intracerebral Hemorrhage by Regulating Neuroinflammation
por: Guo, Mengtian, et al.
Publicado: (2023)

Intracerebral Hemorrhage Progression Score: A Novel Risk Score to Predict Neurological Deterioration after Intracerebral Hemorrhage
por: Ji, Ruijun, et al.
Publicado: (2022)

Neuroinflammation after Intracerebral Hemorrhage and Potential Therapeutic Targets
por: Tschoe, Christine, et al.
Publicado: (2020)

Dysregulation of microRNA and Intracerebral Hemorrhage: Roles in Neuroinflammation
por: Kashif, Hisham, et al.
Publicado: (2021)

TREM2 improves neurological dysfunction and attenuates neuroinflammation, TLR signaling and neuronal apoptosis in the acute phase of intracerebral hemorrhage
por: Liu, Sidan, et al.
Publicado: (2022)

Neuroinflammation of microglia polarization in intracerebral hemorrhage and its potential targets for intervention
por: Yang, Guoqiang, et al.
Publicado: (2022)

Gut Microbiota Dysbiosis Induced by Intracerebral Hemorrhage Aggravates Neuroinflammation in Mice
por: Yu, Xiaobo, et al.
Publicado: (2021)

Intranasal insulin ameliorates neurological impairment after intracerebral hemorrhage in mice
por: Zhu, Yuan, et al.
Publicado: (2021)

Artemisinin upregulates neural cell adhesion molecule L1 to attenuate neurological deficits after intracerebral hemorrhage in mice
por: Wang, Jianjiang, et al.
Publicado: (2022)

Cardiovascular effects of urocortin 2 and urocortin 3 in patients with chronic heart failure
por: Stirrat, Colin G., et al.
Publicado: (2016)

The pivotal role of the NLRC4 inflammasome in neuroinflammation after intracerebral hemorrhage in rats
por: Gan, Hui, et al.
Publicado: (2021)

Microglial replacement in the aged brain restricts neuroinflammation following intracerebral hemorrhage
por: Li, Xiuping, et al.
Publicado: (2022)

Angiopoietin-Like 4 Attenuates Brain Edema and Neurological Deficits in a Mouse Model of Experimental Intracerebral Hemorrhage
por: Qiu, Zhandong, et al.
Publicado: (2018)

Moderate Ethanol Pre-treatment Mitigates ICH-Induced Injury via ER Stress Modulation in Rats
por: Lin, Peter Bor-Chian, et al.
Publicado: (2021)

Prediction of Neurological Deterioration After Intracerebral Hemorrhage: The SIGNALS Score
por: He, Quanwei, et al.
Publicado: (2022)

Lymphocyte-to-Monocyte Ratio Is an Independent Predictor for Neurological Deterioration and 90-Day Mortality in Spontaneous Intracerebral Hemorrhage
por: Qi, Haijun, et al.
Publicado: (2018)

MicroRNAs modulate neuroinflammation after intracerebral hemorrhage: Prospects for new therapy
por: Xia, Siqi, et al.
Publicado: (2022)

Urocortins in the mammalian endocrine system
por: Squillacioti, Caterina, et al.
Publicado: (2019)

Exploring the Role of Urocortin in Osteoporosis
por: Ismail, Omar M, et al.
Publicado: (2023)

Linking stress with urocortin in rats
por: Balraj, Manikandan, et al.
Publicado: (2023)

Treatment of Naoxueshu Promotes Improvement of Hematoma Absorption and Neurological Function in Acute Intracerebral Hemorrhage Patients
por: Song, Juexian, et al.
Publicado: (2018)

Genetic Polymorphisms Associated with Spontaneous Intracerebral Hemorrhage
por: Chen, Yi-Chun, et al.
Publicado: (2018)

The Influence of Oxidative Stress on Neurological Outcomes in Spontaneous Intracerebral Hemorrhage
por: Masomi-Bornwasser, Julia, et al.
Publicado: (2021)

Early spot sign is associated with functional outcomes in primary intracerebral hemorrhage survivors
por: Tseng, Wen-Che, et al.
Publicado: (2021)

Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin
por: Srodulski, Sarah, et al.
Publicado: (2014)

Mild Respiratory COVID-Induced Neuroinflammation Causes Neurological Deficits
por: Yang, Junlin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_oa7vek8poub2iin2lj497js07e