Understanding the physiological roles of the neuronal calcium sensor proteins

Calcium signalling plays a crucial role in the control of neuronal function and plasticity. Changes in neuronal Ca(2+ )concentration are detected by Ca(2+)-binding proteins that can interact with and regulate target proteins to modify their function. Members of the neuronal calcium sensor (NCS) prot...

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Detalles Bibliográficos
Autores principales: Burgoyne, Robert D, Haynes, Lee P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271974/
https://www.ncbi.nlm.nih.gov/pubmed/22269068
http://dx.doi.org/10.1186/1756-6606-5-2
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author Burgoyne, Robert D
Haynes, Lee P
author_facet Burgoyne, Robert D
Haynes, Lee P
author_sort Burgoyne, Robert D
collection PubMed
description Calcium signalling plays a crucial role in the control of neuronal function and plasticity. Changes in neuronal Ca(2+ )concentration are detected by Ca(2+)-binding proteins that can interact with and regulate target proteins to modify their function. Members of the neuronal calcium sensor (NCS) protein family have multiple non-redundant roles in the nervous system. Here we review recent advances in the understanding of the physiological roles of the NCS proteins and the molecular basis for their specificity.
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spelling pubmed-32719742012-02-04 Understanding the physiological roles of the neuronal calcium sensor proteins Burgoyne, Robert D Haynes, Lee P Mol Brain Review Calcium signalling plays a crucial role in the control of neuronal function and plasticity. Changes in neuronal Ca(2+ )concentration are detected by Ca(2+)-binding proteins that can interact with and regulate target proteins to modify their function. Members of the neuronal calcium sensor (NCS) protein family have multiple non-redundant roles in the nervous system. Here we review recent advances in the understanding of the physiological roles of the NCS proteins and the molecular basis for their specificity. BioMed Central 2012-01-23 /pmc/articles/PMC3271974/ /pubmed/22269068 http://dx.doi.org/10.1186/1756-6606-5-2 Text en Copyright ©2012 Burgoyne and Haynes; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Burgoyne, Robert D
Haynes, Lee P
Understanding the physiological roles of the neuronal calcium sensor proteins
title Understanding the physiological roles of the neuronal calcium sensor proteins
title_full Understanding the physiological roles of the neuronal calcium sensor proteins
title_fullStr Understanding the physiological roles of the neuronal calcium sensor proteins
title_full_unstemmed Understanding the physiological roles of the neuronal calcium sensor proteins
title_short Understanding the physiological roles of the neuronal calcium sensor proteins
title_sort understanding the physiological roles of the neuronal calcium sensor proteins
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3271974/
https://www.ncbi.nlm.nih.gov/pubmed/22269068
http://dx.doi.org/10.1186/1756-6606-5-2
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