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Noradrenergic α(1) Receptor Antagonist Treatment Attenuates Positive Subjective Effects of Cocaine in Humans: A Randomized Trial

BACKGROUND: Preclinical research implicates dopaminergic and noradrenergic mechanisms in mediating the reinforcing effects of drugs of abuse, including cocaine. The objective of this study was to evaluate the impact of treatment with the noradrenergic α(1) receptor antagonist doxazosin on the positi...

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Detalles Bibliográficos
Autores principales:	Newton, Thomas F., De La Garza, Richard, Brown, Gregory, Kosten, Thomas R., Mahoney, James J., Haile, Colin N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272014/ https://www.ncbi.nlm.nih.gov/pubmed/22319592 http://dx.doi.org/10.1371/journal.pone.0030854

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