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Diet and Energy-Sensing Inputs Affect TorC1-Mediated Axon Misrouting but Not TorC2-Directed Synapse Growth in a Drosophila Model of Tuberous Sclerosis
The Target of Rapamycin (TOR) growth regulatory system is influenced by a number of different inputs, including growth factor signaling, nutrient availability, and cellular energy levels. While the effects of TOR on cell and organismal growth have been well characterized, this pathway also has profo...
Autores principales: | Dimitroff, Brian, Howe, Katie, Watson, Adrienne, Campion, Bridget, Lee, Hyun-Gwan, Zhao, Na, O'Connor, Michael B., Neufeld, Thomas P., Selleck, Scott B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272037/ https://www.ncbi.nlm.nih.gov/pubmed/22319582 http://dx.doi.org/10.1371/journal.pone.0030722 |
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