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Successful Shortening of Tuberculosis Treatment Using Adjuvant Host-Directed Therapy with FDA-Approved Phosphodiesterase Inhibitors in the Mouse Model
Global control of tuberculosis (TB), an infectious disease that claims nearly 2 million lives annually, is hindered by the long duration of chemotherapy required for curative treatment. Lack of adherence to this intense treatment regimen leads to poor patient outcomes, development of new or addition...
Autores principales: | Maiga, Mamoudou, Agarwal, Nisheeth, Ammerman, Nicole C., Gupta, Radhika, Guo, Haidan, Maiga, Marama C., Lun, Shichun, Bishai, William R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272040/ https://www.ncbi.nlm.nih.gov/pubmed/22319585 http://dx.doi.org/10.1371/journal.pone.0030749 |
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