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Dynein achieves processive motion using both stochastic and coordinated stepping

Processivity, the ability of single molecules to move continuously along a track, is a fundamental requirement of cargo-transporting molecular motors. Here, we investigate how cytoplasmic dynein, a homodimeric, microtubule-based motor, achieves processive motion. To do this we developed a versatile...

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Detalles Bibliográficos
Autores principales: Qiu, Weihong, Derr, Nathan D., Goodman, Brian S., Villa, Elizabeth, Wu, David, Shih, William, Reck-Peterson, Samara L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272163/
https://www.ncbi.nlm.nih.gov/pubmed/22231401
http://dx.doi.org/10.1038/nsmb.2205

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