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Reversible cell cycle entry in adult kidney podocytes through regulated control of telomerase and Wnt signaling

Mechanisms of epithelial cell renewal remain poorly understood in the mammalian kidney, particularly in the glomerulus, a site of cellular damage in chronic kidney disease. Within the glomerulus, podocytes – differentiated epithelial cells critical for filtration – are thought to lack significant ca...

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Detalles Bibliográficos
Autores principales: Shkreli, Marina, Sarin, Kavita Y., Pech, Matthew F., Papeta, Natalia, Chang, Woody, Brockman, Stephanie A., Cheung, Peggie, Lee, Eunice, Kuhnert, Frank, Olson, Jean L., Kuo, Calvin J., Gharavi, Ali G., D’Agati, Vivette D., Artandi, Steven E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272332/
https://www.ncbi.nlm.nih.gov/pubmed/22138751
http://dx.doi.org/10.1038/nm.2550