Cargando…

Delayed Recognition of Disorders of Sex Development (DSD): A Missed Opportunity for Early Diagnosis of Malignant Germ Cell Tumors

Disorders of sex development (DSD) are defined as a congenital condition in which development of chromosomal, gonadal or anatomical sex is atypical. DSD patients with gonadal dysgenesis or hypovirilization, containing part of the Y chromosome (GBY), have an increased risk for malignant type II germ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hersmus, Remko, Stoop, Hans, White, Stefan J., Drop, Stenvert L. S., Oosterhuis, J. Wolter, Incrocci, Luca, Wolffenbuttel, Katja P., Looijenga, Leendert H. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272341/ https://www.ncbi.nlm.nih.gov/pubmed/22315593 http://dx.doi.org/10.1155/2012/671209

Ejemplares similares

SRY mutation analysis by next generation (deep) sequencing in a cohort of chromosomal Disorders of Sex Development (DSD) patients with a mosaic karyotype
por: Hersmus, Remko, et al.
Publicado: (2012)

A 46,XY Female DSD Patient with Bilateral Gonadoblastoma, a Novel SRY Missense Mutation Combined with a WT1 KTS Splice-Site Mutation
por: Hersmus, Remko, et al.
Publicado: (2012)

Prevalence of c-KIT Mutations in Gonadoblastoma and Dysgerminomas of Patients with Disorders of Sex Development (DSD) and Ovarian Dysgerminomas
por: Hersmus, Remko, et al.
Publicado: (2012)

VASA mRNA (DDX4) detection is more specific than immunohistochemistry using poly- or monoclonal antibodies for germ cells in the male urogenital tract
por: Boellaard, Willem P.A., et al.
Publicado: (2017)

Application of the New Classification on Patients with a Disorder of Sex Development in Indonesia
por: Juniarto, A. Zulfa, et al.
Publicado: (2012)

c-MET receptor as potential biomarker and target molecule for malignant testicular germ cell tumors
por: Scheri, Katia Corano, et al.
Publicado: (2018)

Correction: c-MET receptor as potential biomarker and target molecule for malignant testicular germ cell tumors
por: Scheri, Katia Corano, et al.
Publicado: (2018)

Gender change and stigmatization in late-treated Indonesian children, adolescent, and adult patients with DSD
por: Ediati, Annastasia, et al.
Publicado: (2015)

Molecular heterogeneity and early metastatic clone selection in testicular germ cell cancer development
por: Dorssers, Lambert C. J., et al.
Publicado: (2019)

Napabucasin overcomes cisplatin resistance in ovarian germ cell tumor-derived cell line by inhibiting cancer stemness
por: Schmidtova, Silvia, et al.
Publicado: (2020)

DICER1 RNase IIIb domain mutations are infrequent in testicular germ cell tumours
por: de Boer, Carmela M, et al.
Publicado: (2012)

Imprints and DPPA3 are bypassed during pluripotency- and differentiation-coupled methylation reprogramming in testicular germ cell tumors
por: Killian, J. Keith, et al.
Publicado: (2016)

Novel Associations in Disorders of Sex Development: Findings From the I-DSD Registry
por: Cox, Kathryn, et al.
Publicado: (2014)

Glycolipids of human primary testicular germ cell tumours.
por: Olie, R. A., et al.
Publicado: (1996)

Intratubular germ cell neoplasia of the human testis: heterogeneous protein expression and relation to invasive potential
por: Mitchell, Rod T, et al.
Publicado: (2014)

Accurate primary germ cell cancer diagnosis using serum based microRNA detection (ampTSmiR test)
por: van Agthoven, Ton, et al.
Publicado: (2016)

Predicting Gonadal Germ Cell Cancer in People with Disorders of Sex Development; Insights from Developmental Biology
por: Looijenga, Leendert H. J., et al.
Publicado: (2019)

Ectopic activation of WNT signaling in human embryonal carcinoma cells and its effects in short- and long-term in vitro culture
por: Atlasi, Yaser, et al.
Publicado: (2019)

Genomic copy number and expression patterns in testicular germ cell tumours
por: McIntyre, A, et al.
Publicado: (2007)

Do Surgical Interventions Influence Psychosexual and Cosmetic Outcomes in Women with Disorders of Sex Development?
por: Callens, Nina, et al.
Publicado: (2012)

Human Germ Cell Tumors are Developmental Cancers: Impact of Epigenetics on Pathobiology and Clinic
por: Lobo, João, et al.
Publicado: (2019)

Whole exome sequencing combined with linkage analysis identifies a novel 3 bp deletion in NR5A1
por: Eggers, Stefanie, et al.
Publicado: (2015)

Screening for cancers with a good prognosis: The case of testicular germ cell cancer
por: Heijnsdijk, Eveline A. M., et al.
Publicado: (2021)

Mechanisms of TP53 Pathway Inactivation in Embryonic and Somatic Cells—Relevance for Understanding (Germ Cell) Tumorigenesis
por: Timmerman, Dennis M., et al.
Publicado: (2021)

microRNA-371a-3p as informative biomarker for the follow-up of testicular germ cell cancer patients
por: van Agthoven, Ton, et al.
Publicado: (2017)

Prediction of relapse in stage I testicular germ cell tumor patients on surveillance: investigation of biomarkers
por: Lobo, João, et al.
Publicado: (2020)

Etiology and early pathogenesis of malignant testicular germ cell tumors: towards possibilities for preinvasive diagnosis
por: Elzinga-Tinke, Jenny E, et al.
Publicado: (2015)

Expression of Intermediate Filaments in the Developing Testis and Testicular Germ Cell Cancer
por: Camacho-Moll, Maria E., et al.
Publicado: (2022)

The MicroRNA-371 Family as Plasma Biomarkers for Monitoring Undifferentiated and Potentially Malignant Human Pluripotent Stem Cells in Teratoma Assays
por: Salvatori, Daniela C.F., et al.
Publicado: (2018)

Diagnosis of DSD in Children—Development of New Tools for a Structured Diagnostic and Information Management Program within the Empower-DSD Study
por: Wechsung, Katja, et al.
Publicado: (2022)

Human testicular germ cell tumours express inhibin subunits, activin receptors and follistatin mRNAs.
por: van Schaik, R. H., et al.
Publicado: (1997)

Allelic losses in carcinoma in situ and testicular germ cell tumours of adolescents and adults: evidence suggestive of the linear progression model
por: Faulkner, S W, et al.
Publicado: (2000)

Holistic management of DSD
por: Brain, Caroline E., et al.
Publicado: (2010)

Lack of Bcl10 mutations in testicular germ cell tumours and derived cell lines
por: Schothorst, E M van, et al.
Publicado: (1999)

NR5A1 gene variants repress the ovarian‐specific WNT signaling pathway in 46,XX disorders of sex development patients
por: Knarston, Ingrid M., et al.
Publicado: (2018)

Clinical utility of plasma miR‐371a‐3p in germ cell tumors
por: Mego, Michal, et al.
Publicado: (2018)

Disorders of sex development (DSD) web-based information: quality survey of DSD team websites
por: Ernst, Michelle M., et al.
Publicado: (2019)

Etiology and Clinical Presentation of Disorders of Sex Development in Kenyan Children and Adolescents
por: Amolo, Prisca, et al.
Publicado: (2019)

Under-reported aspects of diagnosis and treatment addressed in the Dutch-Flemish guideline for comprehensive diagnostics in disorders/differences of sex development
por: van Bever, Yolande, et al.
Publicado: (2020)

Malignant Germ Cell Tumors and Their Precursor Gonadal Lesions in Patients with XY-DSD: A Case Series and Review of the Literature
por: Steinmacher, Sahra, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tdivckb02k8iooufv95ip9vn7g