Cargando…
Head swivel on the ribosome facilitates translocation via intra-subunit tRNA hybrid sites
The elongation cycle of protein synthesis involves the delivery of aminoacyl-tRNAs to the A-site of the ribosome, followed by peptide-bond formation and translocation of the tRNAs through the ribosome to reopen the A-site(1,2). The translocation reaction is catalyzed by elongation factor G (EF-G) in...
Autores principales: | Ratje, Andreas H., Loerke, Justus, Mikolajka, Aleksandra, Brünner, Matthias, Hildebrand, Peter W., Starosta, Agata L., Dönhöfer, Alexandra, Connell, Sean R., Fucini, Paola, Mielke, Thorsten, Whitford, Paul C., Onuchic, Jose’ N, Yu, Yanan, Sanbonmatsu, Karissa Y., Hartmann, Roland K., Penczek, Pawel A., Wilson, Daniel N., Spahn, Christian M.T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272701/ https://www.ncbi.nlm.nih.gov/pubmed/21124459 http://dx.doi.org/10.1038/nature09547 |
Ejemplares similares
-
Connecting the Kinetics and Energy Landscape of tRNA Translocation on the Ribosome
por: Whitford, Paul C., et al.
Publicado: (2013) -
tRNA Translocation by the Eukaryotic 80S Ribosome and the Impact of GTP Hydrolysis
por: Flis, Julia, et al.
Publicado: (2018) -
Structural insights into ribosomal rescue by Dom34 and Hbs1 at near-atomic resolution
por: Hilal, Tarek, et al.
Publicado: (2016) -
SMOG@ctbp: simplified deployment of structure-based models in GROMACS
por: Noel, Jeffrey K., et al.
Publicado: (2010) -
Visualization of Trna Movements on the Escherichia coli 70s Ribosome during the Elongation Cycle
por: Agrawal, Rajendra K., et al.
Publicado: (2000)