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An Angiotensin II Type 1 Receptor Blocker Prevents Renal Injury via Inhibition of the Notch Pathway in Ins2 Akita Diabetic Mice

Recently, it has been reported that the Notch pathway is involved in the pathogenesis of diabetic nephropathy. In this study, we investigated the activation of the Notch pathway in Ins2 Akita diabetic mouse (Akita mouse) and the effects of telmisartan, an angiotensin II type1 receptor blocker, on th...

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Detalles Bibliográficos
Autores principales:	Koshizaka, Masaya, Takemoto, Minoru, Sato, Seiya, Tokuyama, Hirotake, Fujimoto, Masaki, Okabe, Emiko, Ishibashi, Ryoichi, Ishikawa, Takahiro, Tsurutani, Yuya, Onishi, Shunichiro, Mezawa, Morito, He, Peng, Honjo, Satoshi, Ueda, Shiro, Saito, Yasushi, Yokote, Koutaro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272808/ https://www.ncbi.nlm.nih.gov/pubmed/22319521 http://dx.doi.org/10.1155/2012/159874

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